diff --git a/lib/options.c b/lib/options.c
index 7f7b51e1..dd9f7180 100644
--- a/lib/options.c
+++ b/lib/options.c
@@ -271,7 +271,7 @@ int mosquitto_opts_set(struct mosquitto *mosq, enum mosq_opt_t option, void *val
 #ifdef WITH_TLS
 			mosq->ssl_ctx = (SSL_CTX *)value;
 			if(mosq->ssl_ctx){
-#if OPENSSL_VERSION_NUMBER >= 0x10100000L
+#if (OPENSSL_VERSION_NUMBER >= 0x10100000L) && !defined(LIBRESSL_VERSION_NUMBER)
 				SSL_CTX_up_ref(mosq->ssl_ctx);
 #else
 				CRYPTO_add(&(mosq->ssl_ctx)->references, 1, CRYPTO_LOCK_SSL_CTX);